Vitamin B12 Injection
Vitamin B12 Injection
[component[The main ingredient of this product is vitamin B12.
[character]This product is a clear liquid from pink to red.
[indication]This product is suitable for megaloblastic anemia caused by lack of internal factors, and also for the auxiliary treatment of subacute combined degenerative nervous system diseases, such as neuritis.
[Specifications] 1ml:0.5mg; 1ml:1mg
[Usage and dosage]
Intramuscular injection. Adults: 0.025-0.1mg (0.05-0.2 tubes) one day or 0.05-0.2mg (0.1-0.4 tubes) every other day for 2 weeks. When used for neuritis, the dosage can be increased accordingly. This product can also be used for acupoint sealing.
Adverse reactions
The intramuscular injection can occasionally cause skin rash, pruritus, diarrhea and allergic asthma, but the incidence is low. Very few people have allergic shock.
1. It can cause allergic reaction, even anaphylactic shock, and should not be abused.
2. When conditions permit, the concentration of vitamin B12 in blood should be monitored during the course of medication.
3. Hyperuricemia may occur in gout patients using this product.
4. For the treatment of giant cell anemia, blood potassium should be checked in the first 48 hours to prevent hypokalemia.
Drug interaction
Aminosalicylic acid and chloramphenicol can weaken the effect of this product.
[pharmacological action ]
This product is an anti anemia drug. Vitamin B12 participates in methyl conversion and folic acid metabolism in the body, and promotes the conversion of 5-methyltetrahydrofolate to tetrahydrofolate. When lacking, it will lead to DNA synthesis disorder and affect the maturation of red blood cells. This product also promotes the conversion of methylmalonic acid into succinic acid and participates in the tricarboxylic acid cycle. This effect is related to the synthesis of nerve myelin lipids and the maintenance of functional integrity of myelinated nerve fibers. The neural damage of vitamin B12 deficiency may be related to this.
[Pharmacokinetics]
After intramuscular injection, the absorption was rapid and complete, and the blood concentration reached the peak value about 1 hour. It is widely distributed in the body, but mainly stored in the liver. The total adult storage is 4-5mg. Most of them are excreted by kidney in 8 hours. The greater the dose, the more excreted.
[Storage method]
Protect from light and store in a closed place.
[term of validity]
36 months
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